The Alternative Press Expo is a fun, local SF show that is mostly local creators. It's never too crowded but there is a lot of great talent to see and you generally have a better chance to chat it up with people. Remember, if you attended Comic-Con 2009, your badge from that show is FREE admission to APE so why not drop by?
P.S. Oh, and come by and say "Hi" to us if you do. =)